BDBM50164389 CHEMBL3799181

SMILES: CCNC(=O)c1c(C)sc2nc(cc(=O)n12)C(C)c1cccc(c1F)C(F)(F)F

InChI Key: InChIKey=XVXXBLCNXUKTRD-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164389   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NR1/NR2A (Homo sapiens (Human))	BDBM50164389 (CHEMBL3799181) Show SMILES CCNC(=O)c1c(C)sc2nc(cc(=O)n12)C(C)c1cccc(c1F)C(F)(F)F Show InChI InChI=1S/C19H17F4N3O2S/c1-4-24-17(28)16-10(3)29-18-25-13(8-14(27)26(16)18)9(2)11-6-5-7-12(15(11)20)19(21,22)23/h5-9H,4H2,1-3H3,(H,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co. Ltd. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...				J Med Chem 59: 2760-79 (2016) BindingDB Entry DOI: 10.7270/Q2N87CQW
					More data for this Ligand-Target Pair