BDBM50164393 CHEMBL3799654

SMILES: CCNC(=O)c1c(C)sc2nc(Cc3cccc(C#N)c3F)cc(=O)n12

InChI Key: InChIKey=YKSHENBJFIOPKN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NR1/NR2A (Homo sapiens (Human))	BDBM50164393 (CHEMBL3799654) Show SMILES CCNC(=O)c1c(C)sc2nc(Cc3cccc(C#N)c3F)cc(=O)n12 Show InChI InChI=1S/C18H15FN4O2S/c1-3-21-17(25)16-10(2)26-18-22-13(8-14(24)23(16)18)7-11-5-4-6-12(9-20)15(11)19/h4-6,8H,3,7H2,1-2H3,(H,21,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co. Ltd. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...				J Med Chem 59: 2760-79 (2016) BindingDB Entry DOI: 10.7270/Q2N87CQW
					More data for this Ligand-Target Pair