BDBM50164403 CHEMBL3798166

SMILES: CCN(Cc1cc(=O)n2c(C3CCC3)c(C)sc2n1)c1ccc(F)cc1

InChI Key: InChIKey=ZJGHZRKUJXMSAA-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164403   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GRIA2 (Homo sapiens (Human))	BDBM50164403 (CHEMBL3798166) Show SMILES CCN(Cc1cc(=O)n2c(C3CCC3)c(C)sc2n1)c1ccc(F)cc1 Show InChI InChI=1S/C20H22FN3OS/c1-3-23(17-9-7-15(21)8-10-17)12-16-11-18(25)24-19(14-5-4-6-14)13(2)26-20(24)22-16/h7-11,14H,3-6,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co. Ltd. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GluA2 AMPAR flop isomer expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator dye ba...				J Med Chem 59: 2760-79 (2016) BindingDB Entry DOI: 10.7270/Q2N87CQW
					More data for this Ligand-Target Pair
NR1/NR2A (Homo sapiens (Human))	BDBM50164403 (CHEMBL3798166) Show SMILES CCN(Cc1cc(=O)n2c(C3CCC3)c(C)sc2n1)c1ccc(F)cc1 Show InChI InChI=1S/C20H22FN3OS/c1-3-23(17-9-7-15(21)8-10-17)12-16-11-18(25)24-19(14-5-4-6-14)13(2)26-20(24)22-16/h7-11,14H,3-6,12H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co. Ltd. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...				J Med Chem 59: 2760-79 (2016) BindingDB Entry DOI: 10.7270/Q2N87CQW
					More data for this Ligand-Target Pair
GRIA2 (Homo sapiens (Human))	BDBM50164403 (CHEMBL3798166) Show SMILES CCN(Cc1cc(=O)n2c(C3CCC3)c(C)sc2n1)c1ccc(F)cc1 Show InChI InChI=1S/C20H22FN3OS/c1-3-23(17-9-7-15(21)8-10-17)12-16-11-18(25)24-19(14-5-4-6-14)13(2)26-20(24)22-16/h7-11,14H,3-6,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.59E+4	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co. Ltd. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GluA2 AMPAR flip isomer expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator dye ba...				J Med Chem 59: 2760-79 (2016) BindingDB Entry DOI: 10.7270/Q2N87CQW
					More data for this Ligand-Target Pair