BDBM50164479 CHEMBL3799325

SMILES: CCN(Cc1cc(=O)n2c(C3CC3)c(C)sc2n1)c1ccc(F)cc1

InChI Key: InChIKey=VEJUWRDUONFHHB-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164479   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NR1/NR2A (Homo sapiens (Human))	BDBM50164479 (CHEMBL3799325) Show SMILES CCN(Cc1cc(=O)n2c(C3CC3)c(C)sc2n1)c1ccc(F)cc1 Show InChI InChI=1S/C19H20FN3OS/c1-3-22(16-8-6-14(20)7-9-16)11-15-10-17(24)23-18(13-4-5-13)12(2)25-19(23)21-15/h6-10,13H,3-5,11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	394	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co. Ltd. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...				J Med Chem 59: 2760-79 (2016) BindingDB Entry DOI: 10.7270/Q2N87CQW
					More data for this Ligand-Target Pair
GRIA2 (Homo sapiens (Human))	BDBM50164479 (CHEMBL3799325) Show SMILES CCN(Cc1cc(=O)n2c(C3CC3)c(C)sc2n1)c1ccc(F)cc1 Show InChI InChI=1S/C19H20FN3OS/c1-3-22(16-8-6-14(20)7-9-16)11-15-10-17(24)23-18(13-4-5-13)12(2)25-19(23)21-15/h6-10,13H,3-5,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co. Ltd. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GluA2 AMPAR flip isomer expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator dye ba...				J Med Chem 59: 2760-79 (2016) BindingDB Entry DOI: 10.7270/Q2N87CQW
					More data for this Ligand-Target Pair
GRIA2 (Homo sapiens (Human))	BDBM50164479 (CHEMBL3799325) Show SMILES CCN(Cc1cc(=O)n2c(C3CC3)c(C)sc2n1)c1ccc(F)cc1 Show InChI InChI=1S/C19H20FN3OS/c1-3-22(16-8-6-14(20)7-9-16)11-15-10-17(24)23-18(13-4-5-13)12(2)25-19(23)21-15/h6-10,13H,3-5,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co. Ltd. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GluA2 AMPAR flop isomer expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator dye ba...				J Med Chem 59: 2760-79 (2016) BindingDB Entry DOI: 10.7270/Q2N87CQW
					More data for this Ligand-Target Pair