BDBM50164545 (2R,3S)-1-(9-Oxo-9H-fluorene-2-carbonyl)-piperazine-2,3-dicarboxylic acid::CHEMBL365515

SMILES: OC(=O)[C@H]1NCCN([C@H]1C(O)=O)C(=O)c1ccc2-c3ccccc3C(=O)c2c1

InChI Key: InChIKey=DZCXTGRGGXYURS-JKSUJKDBSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164545   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50164545 ((2R,3S)-1-(9-Oxo-9H-fluorene-2-carbonyl)-piperazin...) Show SMILES OC(=O)[C@H]1NCCN([C@H]1C(O)=O)C(=O)c1ccc2-c3ccccc3C(=O)c2c1 Show InChI InChI=1S/C20H16N2O6/c23-17-13-4-2-1-3-11(13)12-6-5-10(9-14(12)17)18(24)22-8-7-21-15(19(25)26)16(22)20(27)28/h1-6,9,15-16,21H,7-8H2,(H,25,26)(H,27,28)/t15-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...				J Med Chem 48: 2627-37 (2005) Article DOI: 10.1021/jm0492498 BindingDB Entry DOI: 10.7270/Q2FJ2G89
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50164545 ((2R,3S)-1-(9-Oxo-9H-fluorene-2-carbonyl)-piperazin...) Show SMILES OC(=O)[C@H]1NCCN([C@H]1C(O)=O)C(=O)c1ccc2-c3ccccc3C(=O)c2c1 Show InChI InChI=1S/C20H16N2O6/c23-17-13-4-2-1-3-11(13)12-6-5-10(9-14(12)17)18(24)22-8-7-21-15(19(25)26)16(22)20(27)28/h1-6,9,15-16,21H,7-8H2,(H,25,26)(H,27,28)/t15-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.97E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2A expressed in Xeno...				J Med Chem 48: 2627-37 (2005) Article DOI: 10.1021/jm0492498 BindingDB Entry DOI: 10.7270/Q2FJ2G89
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50164545 ((2R,3S)-1-(9-Oxo-9H-fluorene-2-carbonyl)-piperazin...) Show SMILES OC(=O)[C@H]1NCCN([C@H]1C(O)=O)C(=O)c1ccc2-c3ccccc3C(=O)c2c1 Show InChI InChI=1S/C20H16N2O6/c23-17-13-4-2-1-3-11(13)12-6-5-10(9-14(12)17)18(24)22-8-7-21-15(19(25)26)16(22)20(27)28/h1-6,9,15-16,21H,7-8H2,(H,25,26)(H,27,28)/t15-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2B expressed in Xeno...				J Med Chem 48: 2627-37 (2005) Article DOI: 10.1021/jm0492498 BindingDB Entry DOI: 10.7270/Q2FJ2G89
					More data for this Ligand-Target Pair