BDBM50164588 1-[1-(2-Chloro-phenyl)-cyclopropyl]-6-fluoro-2-methyl-1,2,3,4-tetrahydro-isoquinolin-7-ol::CHEMBL192788
SMILES: CN1CCc2cc(F)c(O)cc2C1C1(CC1)c1ccccc1Cl
InChI Key: InChIKey=AXNBRAABOINRNO-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Dopamine D5 receptor (Homo sapiens (Human)-RAT) | BDBM50164588 (1-[1-(2-Chloro-phenyl)-cyclopropyl]-6-fluoro-2-met...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ G. D'Annunzio Curated by ChEMBL | Assay Description Inhibitory constant for Dopamine receptor D1-like | J Med Chem 48: 2646-54 (2005) Article DOI: 10.1021/jm040889k BindingDB Entry DOI: 10.7270/Q2QR4XW2 | |||||||||||
More data for this Ligand-Target Pair |