BDBM50164640 CHEMBL190609::[[[[3-azido-5-(5-methyl-2,4-dioxo-1H-pyrimidin-1-yl)-tetrahydrofuran-2-yl]methoxy-boranyl-phosphoryl]oxy-hydroxy-phosphoryl]-difluoro-methyl]phosphonic acid

SMILES: [BH3-]P(=O)(OCC1OC(CC1N=[N+]=[N-])n1cc(C)c(=O)[nH]c1=O)OP([O-])(=O)C(F)(F)P([O-])([O-])=O

InChI Key: InChIKey=IGNYNYJUOBXSFG-UHFFFAOYSA-K

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164640   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50164640 (CHEMBL190609 | [[[[3-azido-5-(5-methyl-2,4-dioxo-1...) Show SMILES [BH3-]P(=O)(OCC1OC(CC1N=[N+]=[N-])n1cc(C)c(=O)[nH]c1=O)OP([O-])(=O)C(F)(F)P([O-])([O-])=O Show InChI InChI=1S/C11H18BF2N5O11P3/c1-5-3-19(10(21)16-9(5)20)8-2-6(17-18-15)7(29-8)4-28-33(12,27)30-32(25,26)11(13,14)31(22,23)24/h3,6-8H,2,4H2,1,12H3,(H,25,26)(H,16,20,21)(H2,22,23,24)/q-1/p-3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biota, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against HIV-1 reverse transcriptase				J Med Chem 48: 2695-700 (2005) Article DOI: 10.1021/jm040101y BindingDB Entry DOI: 10.7270/Q2G73FG5
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