BDBM50164643 ({[({[5-(4-amino-5-fluoro-2-oxo-1,2-dihydropyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy}(boranuidyl)phosphoryl)oxy]phosphinato}difluoromethyl)phosphonate::CHEMBL265235

SMILES: [BH3-]P(=O)(OCC1OC(CS1)n1cc(F)c(N)nc1=O)OP([O-])(=O)C(F)(F)P([O-])([O-])=O

InChI Key: InChIKey=ODIIOEXKOIOASA-UHFFFAOYSA-K

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164643   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50164643 (({[({[5-(4-amino-5-fluoro-2-oxo-1,2-dihydropyrimid...) Show SMILES [BH3-]P(=O)(OCC1OC(CS1)n1cc(F)c(N)nc1=O)OP([O-])(=O)C(F)(F)P([O-])([O-])=O Show InChI InChI=1S/C9H15BF3N3O10P3S/c10-29(23,26-28(21,22)9(12,13)27(18,19)20)24-2-6-25-5(3-30-6)16-1-4(11)7(14)15-8(16)17/h1,5-6H,2-3H2,10H3,(H,21,22)(H2,14,15,17)(H2,18,19,20)/q-1/p-3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biota, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against HIV-1 reverse transcriptase				J Med Chem 48: 2695-700 (2005) Article DOI: 10.1021/jm040101y BindingDB Entry DOI: 10.7270/Q2G73FG5
					More data for this Ligand-Target Pair