BDBM50164699 (3H-Benzoimidazol-5-yl)-[4-(3-methoxy-phenoxy)-5-trifluoromethyl-pyrimidin-2-yl]-amine::CHEMBL371792

SMILES: COc1cccc(Oc2nc(Nc3ccc4nc[nH]c4c3)ncc2C(F)(F)F)c1

InChI Key: InChIKey=FJKZGKXETROXIZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50164699 ((3H-Benzoimidazol-5-yl)-[4-(3-methoxy-phenoxy)-5-t...) Show SMILES COc1cccc(Oc2nc(Nc3ccc4nc[nH]c4c3)ncc2C(F)(F)F)c1 Show InChI InChI=1S/C19H14F3N5O2/c1-28-12-3-2-4-13(8-12)29-17-14(19(20,21)22)9-23-18(27-17)26-11-5-6-15-16(7-11)25-10-24-15/h2-10H,1H3,(H,24,25)(H,23,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibitory concentration against Cyclin dependent kinase 1				Bioorg Med Chem Lett 15: 1973-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.076 BindingDB Entry DOI: 10.7270/Q2610ZT5
					More data for this Ligand-Target Pair