BDBM50164723 (3H-Benzoimidazol-5-yl)-[4-(4-chloro-phenoxy)-5-trifluoromethyl-pyrimidin-2-yl]-amine::CHEMBL195595

SMILES: FC(F)(F)c1cnc(Nc2ccc3nc[nH]c3c2)nc1Oc1ccc(Cl)cc1

InChI Key: InChIKey=WURCWKFIZKHYDK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164723   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50164723 ((3H-Benzoimidazol-5-yl)-[4-(4-chloro-phenoxy)-5-tr...) Show SMILES FC(F)(F)c1cnc(Nc2ccc3nc[nH]c3c2)nc1Oc1ccc(Cl)cc1 Show InChI InChI=1S/C18H11ClF3N5O/c19-10-1-4-12(5-2-10)28-16-13(18(20,21)22)8-23-17(27-16)26-11-3-6-14-15(7-11)25-9-24-14/h1-9H,(H,24,25)(H,23,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	252	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibitory concentration against Cyclin dependent kinase 1				Bioorg Med Chem Lett 15: 1973-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.076 BindingDB Entry DOI: 10.7270/Q2610ZT5
					More data for this Ligand-Target Pair