BDBM50164732 CHEMBL3798655

SMILES: NC(=O)c1cc(Cl)cn(Cc2cccc(c2)C#N)c1=N

InChI Key: InChIKey=DYAJWGPPARHWFY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164732   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50164732 (CHEMBL3798655) Show SMILES NC(=O)c1cc(Cl)cn(Cc2cccc(c2)C#N)c1=N Show InChI InChI=1S/C14H11ClN4O/c15-11-5-12(14(18)20)13(17)19(8-11)7-10-3-1-2-9(4-10)6-16/h1-5,8,17H,7H2,(H2,18,20)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...				J Med Chem 59: 2989-3002 (2016) BindingDB Entry DOI: 10.7270/Q20G3N2B
					More data for this Ligand-Target Pair