BDBM50164773 CHEMBL3799127

SMILES: CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(N)cc1

InChI Key: InChIKey=SSJVLCZVKGGJJO-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (WDR5) (Homo sapiens (Human))	BDBM50164773 (CHEMBL3799127) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(N)cc1 Show InChI InChI=1S/C24H24F3N5O2/c1-31-8-10-32(11-9-31)21-7-4-16(15-2-5-17(28)6-3-15)12-20(21)30-23(34)18-14-29-22(33)13-19(18)24(25,26)27/h2-7,12-14H,8-11,28H2,1H3,(H,29,33)(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair