BDBM50164973 (R)-2-[3-(4-Fluoro-phenoxy)-benzoyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (4-chloro-phenyl)-amide::CHEMBL195151

SMILES: Fc1ccc(Oc2cccc(c2)C(=O)N2Cc3ccccc3C[C@@H]2C(=O)Nc2ccc(Cl)cc2)cc1

InChI Key: InChIKey=IVDSFDCOHULLMD-HHHXNRCGSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164973   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50164973 ((R)-2-[3-(4-Fluoro-phenoxy)-benzoyl]-1,2,3,4-tetra...) Show SMILES Fc1ccc(Oc2cccc(c2)C(=O)N2Cc3ccccc3C[C@@H]2C(=O)Nc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C29H22ClFN2O3/c30-22-8-12-24(13-9-22)32-28(34)27-17-19-4-1-2-5-21(19)18-33(27)29(35)20-6-3-7-26(16-20)36-25-14-10-23(31)11-15-25/h1-16,27H,17-18H2,(H,32,34)/t27-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	590	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTR				Bioorg Med Chem Lett 15: 2087-91 (2005) Article DOI: 10.1016/j.bmcl.2005.02.041 BindingDB Entry DOI: 10.7270/Q2J965WP
					More data for this Ligand-Target Pair