BDBM50165063 9-(2-Benzenesulfonylmethyl-benzyl)-6-furan-2-yl-9H-purin-2-ylamine::CHEMBL195503
SMILES: Nc1nc(-c2ccco2)c2ncn(Cc3ccccc3CS(=O)(=O)c3ccccc3)c2n1
InChI Key: InChIKey=LZFWVIFXSFJRRE-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50165063 (9-(2-Benzenesulfonylmethyl-benzyl)-6-furan-2-yl-9H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranes | Bioorg Med Chem Lett 15: 2119-22 (2005) Article DOI: 10.1016/j.bmcl.2005.02.031 BindingDB Entry DOI: 10.7270/Q2542N3H | |||||||||||
More data for this Ligand-Target Pair |