BDBM50165328 2-Phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalene-1,4-dione::CHEMBL192555

SMILES: O=c1c(nn2n1c1ccccc1[nH]c2=O)-c1ccccc1

InChI Key: InChIKey=ZFLBRINMIQTFNB-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50165328   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-1/beta-2/gamma-2 subunit (Rattus norvegicus (Rat))	BDBM50165328 (2-Phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphth...) Show SMILES O=c1c(nn2n1c1ccccc1[nH]c2=O)-c1ccccc1 Show InChI InChI=1S/C15H10N4O2/c20-14-13(10-6-2-1-3-7-10)17-19-15(21)16-11-8-4-5-9-12(11)18(14)19/h1-9H,(H,16,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha1-beta2-gamma2 expressed in HEK293 cells				J Med Chem 48: 2936-43 (2005) Article DOI: 10.1021/jm0408722 BindingDB Entry DOI: 10.7270/Q2H994QV
					More data for this Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit (Rattus norvegicus (Rat)-RAT)	BDBM50165328 (2-Phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphth...) Show SMILES O=c1c(nn2n1c1ccccc1[nH]c2=O)-c1ccccc1 Show InChI InChI=1S/C15H10N4O2/c20-14-13(10-6-2-1-3-7-10)17-19-15(21)16-11-8-4-5-9-12(11)18(14)19/h1-9H,(H,16,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha5-beta3-gamma2 expressed in HEK293 cells				J Med Chem 48: 2936-43 (2005) Article DOI: 10.1021/jm0408722 BindingDB Entry DOI: 10.7270/Q2H994QV
					More data for this Ligand-Target Pair
GABA receptor alpha-2/beta-2/gamma-2 subunit (Rattus norvegicus (Rat))	BDBM50165328 (2-Phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphth...) Show SMILES O=c1c(nn2n1c1ccccc1[nH]c2=O)-c1ccccc1 Show InChI InChI=1S/C15H10N4O2/c20-14-13(10-6-2-1-3-7-10)17-19-15(21)16-11-8-4-5-9-12(11)18(14)19/h1-9H,(H,16,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha2-beta2-gamma2 expressed in HEK293 cells				J Med Chem 48: 2936-43 (2005) Article DOI: 10.1021/jm0408722 BindingDB Entry DOI: 10.7270/Q2H994QV
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50165328 (2-Phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphth...) Show SMILES O=c1c(nn2n1c1ccccc1[nH]c2=O)-c1ccccc1 Show InChI InChI=1S/C15H10N4O2/c20-14-13(10-6-2-1-3-7-10)17-19-15(21)16-11-8-4-5-9-12(11)18(14)19/h1-9H,(H,16,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	91.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cells				J Med Chem 50: 5676-84 (2007) Article DOI: 10.1021/jm0708376 BindingDB Entry DOI: 10.7270/Q2SJ1MFX
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50165328 (2-Phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphth...) Show SMILES O=c1c(nn2n1c1ccccc1[nH]c2=O)-c1ccccc1 Show InChI InChI=1S/C15H10N4O2/c20-14-13(10-6-2-1-3-7-10)17-19-15(21)16-11-8-4-5-9-12(11)18(14)19/h1-9H,(H,16,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells				J Med Chem 50: 5676-84 (2007) Article DOI: 10.1021/jm0708376 BindingDB Entry DOI: 10.7270/Q2SJ1MFX
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50165328 (2-Phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphth...) Show SMILES O=c1c(nn2n1c1ccccc1[nH]c2=O)-c1ccccc1 Show InChI InChI=1S/C15H10N4O2/c20-14-13(10-6-2-1-3-7-10)17-19-15(21)16-11-8-4-5-9-12(11)18(14)19/h1-9H,(H,16,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cells				J Med Chem 50: 5676-84 (2007) Article DOI: 10.1021/jm0708376 BindingDB Entry DOI: 10.7270/Q2SJ1MFX
					More data for this Ligand-Target Pair