BDBM50165482 2-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phenyl]-isoindole-1,3-dione::CHEMBL370692

SMILES: O=C1N(C(=O)c2ccccc12)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1

InChI Key: InChIKey=VVHSXBBCHBGZKG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165482   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50165482 (2-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phe...) Show SMILES O=C1N(C(=O)c2ccccc12)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1 Show InChI InChI=1S/C23H15N3O3/c27-21-17-9-2-1-8-16(17)20(24-25-21)13-14-6-5-7-15(12-14)26-22(28)18-10-3-4-11-19(18)23(26)29/h1-12H,13H2,(H,25,27)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
KuDOS Horsham Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)				Bioorg Med Chem Lett 15: 2235-8 (2005) Article DOI: 10.1016/j.bmcl.2005.03.026 BindingDB Entry DOI: 10.7270/Q2QV3M0B
					More data for this Ligand-Target Pair