BDBM50165485 2,2,2-Trifluoro-N-[3-(4-oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phenyl]-acetamide::CHEMBL195464

SMILES: FC(F)(F)C(=O)Nc1cccc(Cc2n[nH]c(=O)c3ccccc23)c1

InChI Key: InChIKey=FQUGYQMEXFENDI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165485   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50165485 (2,2,2-Trifluoro-N-[3-(4-oxo-3,4-dihydro-phthalazin...) Show SMILES FC(F)(F)C(=O)Nc1cccc(Cc2n[nH]c(=O)c3ccccc23)c1 Show InChI InChI=1S/C17H12F3N3O2/c18-17(19,20)16(25)21-11-5-3-4-10(8-11)9-14-12-6-1-2-7-13(12)15(24)23-22-14/h1-8H,9H2,(H,21,25)(H,23,24)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
KuDOS Horsham Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)				Bioorg Med Chem Lett 15: 2235-8 (2005) Article DOI: 10.1016/j.bmcl.2005.03.026 BindingDB Entry DOI: 10.7270/Q2QV3M0B
					More data for this Ligand-Target Pair