BDBM50165487 1-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phenyl]-pyrrole-2,5-dione::CHEMBL363617
SMILES: O=C1C=CC(=O)N1c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1
InChI Key: InChIKey=OKOQVTWKOPFLQX-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human)) | BDBM50165487 (1-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phe...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
KuDOS Horsham Ltd Curated by ChEMBL | Assay Description Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1) | Bioorg Med Chem Lett 15: 2235-8 (2005) Article DOI: 10.1016/j.bmcl.2005.03.026 BindingDB Entry DOI: 10.7270/Q2QV3M0B | |||||||||||
More data for this Ligand-Target Pair |