BDBM50165490 4-[3-(3-Methyl-[1,2,4]oxadiazol-5-yl)-benzyl]-2H-phthalazin-1-one::CHEMBL193918

SMILES: Cc1noc(n1)-c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1

InChI Key: InChIKey=AFGHIKCFBLTHES-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165490   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50165490 (4-[3-(3-Methyl-[1,2,4]oxadiazol-5-yl)-benzyl]-2H-p...) Show SMILES Cc1noc(n1)-c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1 Show InChI InChI=1S/C18H14N4O2/c1-11-19-18(24-22-11)13-6-4-5-12(9-13)10-16-14-7-2-3-8-15(14)17(23)21-20-16/h2-9H,10H2,1H3,(H,21,23)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	189	n/a	n/a	n/a	n/a	n/a	n/a
KuDOS Horsham Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)				Bioorg Med Chem Lett 15: 2235-8 (2005) Article DOI: 10.1016/j.bmcl.2005.03.026 BindingDB Entry DOI: 10.7270/Q2QV3M0B
					More data for this Ligand-Target Pair