BDBM50165523 1-tert-Butyl-3-[1-ethyl-2-(2-methoxy-5-nitro-benzylsulfanyl)-1H-benzoimidazol-5-yl]-urea::CHEMBL366236

SMILES: CCn1c(SCc2cc(ccc2OC)[N+]([O-])=O)nc2cc(NC(=O)NC(C)(C)C)ccc12

InChI Key: InChIKey=SXCKCRFUZUBTGB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50165523 (1-tert-Butyl-3-[1-ethyl-2-(2-methoxy-5-nitro-benzy...) Show SMILES CCn1c(SCc2cc(ccc2OC)[N+]([O-])=O)nc2cc(NC(=O)NC(C)(C)C)ccc12 Show InChI InChI=1S/C22H27N5O4S/c1-6-26-18-9-7-15(23-20(28)25-22(2,3)4)12-17(18)24-21(26)32-13-14-11-16(27(29)30)8-10-19(14)31-5/h7-12H,6,13H2,1-5H3,(H2,23,25,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 619-0216 Curated by ChEMBL					Assay Description Inhibitory concentration against human leutinizing releasing hormone receptor				Bioorg Med Chem Lett 15: 2265-9 (2005) Article DOI: 10.1016/j.bmcl.2005.03.030 BindingDB Entry DOI: 10.7270/Q2GB23K1
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50165523 (1-tert-Butyl-3-[1-ethyl-2-(2-methoxy-5-nitro-benzy...) Show SMILES CCn1c(SCc2cc(ccc2OC)[N+]([O-])=O)nc2cc(NC(=O)NC(C)(C)C)ccc12 Show InChI InChI=1S/C22H27N5O4S/c1-6-26-18-9-7-15(23-20(28)25-22(2,3)4)12-17(18)24-21(26)32-13-14-11-16(27(29)30)8-10-19(14)31-5/h7-12H,6,13H2,1-5H3,(H2,23,25,28)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 619-0216 Curated by ChEMBL					Assay Description Inhibitory concentration against rat leutinizing releasing hormone receptor				Bioorg Med Chem Lett 15: 2265-9 (2005) Article DOI: 10.1016/j.bmcl.2005.03.030 BindingDB Entry DOI: 10.7270/Q2GB23K1
					More data for this Ligand-Target Pair