BDBM50165620 2-(4-(5-(2-chloro-4-(3-(4-methoxyphenyl)acrylamido)phenyl)furan-2-yl)thiazol-2-yl)acetic acid::CHEMBL371702::[4-(5-{2-Chloro-4-[3-(4-methoxy-phenyl)-acryloylamino]-phenyl}-furan-2-yl)-thiazol-2-yl]-acetic acid

SMILES: COc1ccc(\C=C\C(=O)Nc2ccc(-c3ccc(o3)-c3csc(CC(O)=O)n3)c(Cl)c2)cc1

InChI Key: InChIKey=MBJLVXKBXGFRSK-NYYWCZLTSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heparanase (Homo sapiens (Human))	BDBM50165620 (2-(4-(5-(2-chloro-4-(3-(4-methoxyphenyl)acrylamido...) Show SMILES COc1ccc(\C=C\C(=O)Nc2ccc(-c3ccc(o3)-c3csc(CC(O)=O)n3)c(Cl)c2)cc1 Show InChI InChI=1S/C25H19ClN2O5S/c1-32-17-6-2-15(3-7-17)4-11-23(29)27-16-5-8-18(19(26)12-16)21-9-10-22(33-21)20-14-34-24(28-20)13-25(30)31/h2-12,14H,13H2,1H3,(H,27,29)(H,30,31)/b11-4+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
Sharif University of Technology Curated by ChEMBL					Assay Description Inhibition of heparanase				Eur J Med Chem 43: 548-56 (2008) Article DOI: 10.1016/j.ejmech.2007.04.014 BindingDB Entry DOI: 10.7270/Q2PC33KM
					More data for this Ligand-Target Pair
Heparanase (Homo sapiens (Human))	BDBM50165620 (2-(4-(5-(2-chloro-4-(3-(4-methoxyphenyl)acrylamido...) Show SMILES COc1ccc(\C=C\C(=O)Nc2ccc(-c3ccc(o3)-c3csc(CC(O)=O)n3)c(Cl)c2)cc1 Show InChI InChI=1S/C25H19ClN2O5S/c1-32-17-6-2-15(3-7-17)4-11-23(29)27-16-5-8-18(19(26)12-16)21-9-10-22(33-21)20-14-34-24(28-20)13-25(30)31/h2-12,14H,13H2,1H3,(H,27,29)(H,30,31)/b11-4+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Celltech R&D Ltd Curated by ChEMBL					Assay Description In vitro inhibitory concentration against human Heparanase				Bioorg Med Chem Lett 15: 2295-9 (2005) Article DOI: 10.1016/j.bmcl.2005.03.014 BindingDB Entry DOI: 10.7270/Q2BP029G
					More data for this Ligand-Target Pair