BDBM50165778 (R)-7-Benzyl-5-ethyl-3-(4-methoxy-benzyl)-2-phenylethynyl-7,8-dihydro-3H,5H-imidazo[2,1-b]purin-4-one::CHEMBL197049

SMILES: CCN1C2=N[C@H](Cc3ccccc3)CN2c2nc(C#Cc3ccccc3)n(Cc3ccc(OC)cc3)c2C1=O

InChI Key: InChIKey=BGXDBYWYEHSLAU-AREMUKBSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165778   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50165778 ((R)-7-Benzyl-5-ethyl-3-(4-methoxy-benzyl)-2-phenyl...) Show SMILES CCN1C2=N[C@H](Cc3ccccc3)CN2c2nc(C#Cc3ccccc3)n(Cc3ccc(OC)cc3)c2C1=O |t:3| Show InChI InChI=1S/C32H29N5O2/c1-3-35-31(38)29-30(37-22-26(33-32(35)37)20-24-12-8-5-9-13-24)34-28(19-16-23-10-6-4-7-11-23)36(29)21-25-14-17-27(39-2)18-15-25/h4-15,17-18,26H,3,20-22H2,1-2H3/t26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of human phosphodiesterase 5				Bioorg Med Chem Lett 15: 2365-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.083 BindingDB Entry DOI: 10.7270/Q2TM79MQ
					More data for this Ligand-Target Pair