BDBM50165805 4-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,3a,5,7,8-pentaaza-cyclopenta[a]naphthalen-4-yl)-butyric acid::CHEMBL194081

SMILES: Cc1nn(Cc2ccccc2)c(=O)c2nc(CCCC(O)=O)n3nc(cc3c12)-c1ccccc1

InChI Key: InChIKey=GYMVWZYQTHZSRE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165805   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 6 (Bos taurus-Bos taurus (Bovine))	BDBM50165805 (4-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...) Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(CCCC(O)=O)n3nc(cc3c12)-c1ccccc1 Show InChI InChI=1S/C26H23N5O3/c1-17-24-21-15-20(19-11-6-3-7-12-19)29-31(21)22(13-8-14-23(32)33)27-25(24)26(34)30(28-17)16-18-9-4-2-5-10-18/h2-7,9-12,15H,8,13-14,16H2,1H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of bovine Phosphodiesterase 6 (n=2-3)				Bioorg Med Chem Lett 15: 2381-4 (2005) Article DOI: 10.1016/j.bmcl.2005.02.090 BindingDB Entry DOI: 10.7270/Q2K64HK9
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50165805 (4-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...) Show SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(CCCC(O)=O)n3nc(cc3c12)-c1ccccc1 Show InChI InChI=1S/C26H23N5O3/c1-17-24-21-15-20(19-11-6-3-7-12-19)29-31(21)22(13-8-14-23(32)33)27-25(24)26(34)30(28-17)16-18-9-4-2-5-10-18/h2-7,9-12,15H,8,13-14,16H2,1H3,(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 5 (n=2-3)				Bioorg Med Chem Lett 15: 2381-4 (2005) Article DOI: 10.1016/j.bmcl.2005.02.090 BindingDB Entry DOI: 10.7270/Q2K64HK9
					More data for this Ligand-Target Pair