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BDBM50165832 4'-{(R)-1-[4-Methyl-3-(3,3,3-trifluoro-propionylamino)-pyridin-2-ylamino]-ethyl}-biphenyl-2-carboxylic acid methylamide::CHEMBL196352

SMILES: CNC(=O)c1ccccc1-c1ccc(cc1)[C@@H](C)Nc1nccc(C)c1NC(=O)CC(F)(F)F

InChI Key: InChIKey=PLYGOPSRARZLEU-MRXNPFEDSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165832   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bradykinin B1 receptor


(Homo sapiens (Human))		BDBM50165832
PNG
(4'-{(R)-1-[4-Methyl-3-(3,3,3-trifluoro-propionylam...)
Show SMILES CNC(=O)c1ccccc1-c1ccc(cc1)[C@@H](C)Nc1nccc(C)c1NC(=O)CC(F)(F)F
Show InChI InChI=1S/C25H25F3N4O2/c1-15-12-13-30-23(22(15)32-21(33)14-25(26,27)28)31-16(2)17-8-10-18(11-9-17)19-6-4-5-7-20(19)24(34)29-3/h4-13,16H,14H2,1-3H3,(H,29,34)(H,30,31)(H,32,33)/t16-/m1/s1
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Similars
Article
PubMed
 6n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory constant against human Bradykinin receptor B1 expressed in chinese hamster ovary cells

Bioorg Med Chem Lett 15: 2385-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.077
BindingDB Entry DOI: 10.7270/Q2FF3RW1
More data for this
Ligand-Target Pair