BDBM50166025 CHEMBL193040::Naphthalene-2-carboxylic acid [4-((S)-8-methoxy-1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-butyl]-amide

SMILES: COc1ccc2N3CCN(CCCCNC(=O)c4ccc5ccccc5c4)C[C@@H]3CCc2c1

InChI Key: InChIKey=UIDZLCOJXTUNII-VWLOTQADSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50166025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50166025 (CHEMBL193040 | Naphthalene-2-carboxylic acid [4-((...) Show SMILES COc1ccc2N3CCN(CCCCNC(=O)c4ccc5ccccc5c4)C[C@@H]3CCc2c1 Show InChI InChI=1S/C28H33N3O2/c1-33-26-12-13-27-23(19-26)10-11-25-20-30(16-17-31(25)27)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-22(21)18-24/h2-3,6-9,12-13,18-19,25H,4-5,10-11,14-17,20H2,1H3,(H,29,32)/t25-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of [3H]-PD 128907 binding to Dopamine receptor D3 in rat ventral striatum				J Med Chem 48: 3171-81 (2005) Article DOI: 10.1021/jm049031l BindingDB Entry DOI: 10.7270/Q2NZ874W
					More data for this Ligand-Target Pair
Dopamine receptor (RAT)	BDBM50166025 (CHEMBL193040 | Naphthalene-2-carboxylic acid [4-((...) Show SMILES COc1ccc2N3CCN(CCCCNC(=O)c4ccc5ccccc5c4)C[C@@H]3CCc2c1 Show InChI InChI=1S/C28H33N3O2/c1-33-26-12-13-27-23(19-26)10-11-25-20-30(16-17-31(25)27)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-22(21)18-24/h2-3,6-9,12-13,18-19,25H,4-5,10-11,14-17,20H2,1H3,(H,29,32)/t25-/m0/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of [3H]-Spiperone binding to Dopamine receptor D2-like in rat caudate-putamen membrane				J Med Chem 48: 3171-81 (2005) Article DOI: 10.1021/jm049031l BindingDB Entry DOI: 10.7270/Q2NZ874W
					More data for this Ligand-Target Pair
Dopamine D1B (RAT)	BDBM50166025 (CHEMBL193040 | Naphthalene-2-carboxylic acid [4-((...) Show SMILES COc1ccc2N3CCN(CCCCNC(=O)c4ccc5ccccc5c4)C[C@@H]3CCc2c1 Show InChI InChI=1S/C28H33N3O2/c1-33-26-12-13-27-23(19-26)10-11-25-20-30(16-17-31(25)27)15-5-4-14-29-28(32)24-9-8-21-6-2-3-7-22(21)18-24/h2-3,6-9,12-13,18-19,25H,4-5,10-11,14-17,20H2,1H3,(H,29,32)/t25-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1-like in rat brain				J Med Chem 48: 3171-81 (2005) Article DOI: 10.1021/jm049031l BindingDB Entry DOI: 10.7270/Q2NZ874W
					More data for this Ligand-Target Pair