BDBM50166150 (3S,6S)-3-[Bis-(4-fluoro-phenyl)-methoxy]-6-methoxymethoxy-8-methyl-8-aza-bicyclo[3.2.1]octane::CHEMBL365397

SMILES: COCO[C@H]1CC2C[C@@H](CC1N2C)OC(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key: InChIKey=ASVJPCQXPWNHDI-XLCOUGHXSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166150   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50166150 ((3S,6S)-3-[Bis-(4-fluoro-phenyl)-methoxy]-6-methox...) Show SMILES COCO[C@H]1CC2C[C@@H](CC1N2C)OC(c1ccc(F)cc1)c1ccc(F)cc1 |TLB:3:4:11:9.7.8,13:8:11:5.4| Show InChI InChI=1S/C23H27F2NO3/c1-26-19-11-20(13-21(26)22(12-19)28-14-27-2)29-23(15-3-7-17(24)8-4-15)16-5-9-18(25)10-6-16/h3-10,19-23H,11-14H2,1-2H3/t19?,20-,21?,22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamen				J Med Chem 48: 3337-43 (2005) Article DOI: 10.1021/jm0490235 BindingDB Entry DOI: 10.7270/Q25T3M8M
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50166150 ((3S,6S)-3-[Bis-(4-fluoro-phenyl)-methoxy]-6-methox...) Show SMILES COCO[C@H]1CC2C[C@@H](CC1N2C)OC(c1ccc(F)cc1)c1ccc(F)cc1 |TLB:3:4:11:9.7.8,13:8:11:5.4| Show InChI InChI=1S/C23H27F2NO3/c1-26-19-11-20(13-21(26)22(12-19)28-14-27-2)29-23(15-3-7-17(24)8-4-15)16-5-9-18(25)10-6-16/h3-10,19-23H,11-14H2,1-2H3/t19?,20-,21?,22-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from Serotonin transporter of rat caudate putamen				J Med Chem 48: 3337-43 (2005) Article DOI: 10.1021/jm0490235 BindingDB Entry DOI: 10.7270/Q25T3M8M
					More data for this Ligand-Target Pair