BDBM50166258 5-[4-(2-Hydroxy-ethyl)-piperazin-1-yl]-5-[4-(4-methoxy-phenoxy)-phenyl]-pyrimidine-2,4,6-trione::CHEMBL195743

SMILES: COc1ccc(Oc2ccc(cc2)C2(N3CCN(CCO)CC3)C(=O)NC(=O)NC2=O)cc1

InChI Key: InChIKey=OCQPVQCJWDXDLQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50166258 (5-[4-(2-Hydroxy-ethyl)-piperazin-1-yl]-5-[4-(4-met...) Show SMILES COc1ccc(Oc2ccc(cc2)C2(N3CCN(CCO)CC3)C(=O)NC(=O)NC2=O)cc1 Show InChI InChI=1S/C23H26N4O6/c1-32-17-6-8-19(9-7-17)33-18-4-2-16(3-5-18)23(20(29)24-22(31)25-21(23)30)27-12-10-26(11-13-27)14-15-28/h2-9,28H,10-15H2,1H3,(H2,24,25,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital of the Westf£lische Wilhelms-Universit£t Curated by ChEMBL					Assay Description In vitro inhibition of human Matrix metalloprotease 9				J Med Chem 48: 3400-9 (2005) Article DOI: 10.1021/jm049145x BindingDB Entry DOI: 10.7270/Q2NS0VPR
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50166258 (5-[4-(2-Hydroxy-ethyl)-piperazin-1-yl]-5-[4-(4-met...) Show SMILES COc1ccc(Oc2ccc(cc2)C2(N3CCN(CCO)CC3)C(=O)NC(=O)NC2=O)cc1 Show InChI InChI=1S/C23H26N4O6/c1-32-17-6-8-19(9-7-17)33-18-4-2-16(3-5-18)23(20(29)24-22(31)25-21(23)30)27-12-10-26(11-13-27)14-15-28/h2-9,28H,10-15H2,1H3,(H2,24,25,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital of the Westf£lische Wilhelms-Universit£t Curated by ChEMBL					Assay Description In vitro inhibition of human Matrix metalloprotease 2				J Med Chem 48: 3400-9 (2005) Article DOI: 10.1021/jm049145x BindingDB Entry DOI: 10.7270/Q2NS0VPR
					More data for this Ligand-Target Pair