BDBM50166291 3-Methyl-5-{4-[2-(methyl-pyridin-2-yl-amino)-ethoxy]-benzyl}-thiazolidine-2,4-dione::CHEMBL195367

SMILES: CN(CCOc1ccc(Cc2sc(=O)n(C)c2O)cc1)c1ccccn1

InChI Key: InChIKey=PMDAMLBOJSLKAV-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166291   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50166291 (3-Methyl-5-{4-[2-(methyl-pyridin-2-yl-amino)-ethox...) Show SMILES CN(CCOc1ccc(Cc2sc(=O)n(C)c2O)cc1)c1ccccn1 Show InChI InChI=1S/C19H21N3O3S/c1-21(17-5-3-4-10-20-17)11-12-25-15-8-6-14(7-9-15)13-16-18(23)22(2)19(24)26-16/h3-10,23H,11-13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human peroxisome proliferator activated receptor gamma binding				Bioorg Med Chem Lett 15: 2437-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.092 BindingDB Entry DOI: 10.7270/Q2CF9PM8
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50166291 (3-Methyl-5-{4-[2-(methyl-pyridin-2-yl-amino)-ethox...) Show SMILES CN(CCOc1ccc(Cc2sc(=O)n(C)c2O)cc1)c1ccccn1 Show InChI InChI=1S/C19H21N3O3S/c1-21(17-5-3-4-10-20-17)11-12-25-15-8-6-14(7-9-15)13-16-18(23)22(2)19(24)26-16/h3-10,23H,11-13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivation				Bioorg Med Chem Lett 15: 2437-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.092 BindingDB Entry DOI: 10.7270/Q2CF9PM8
					More data for this Ligand-Target Pair