BDBM50166314 6-((3S,5S)-5-((S)-2-cyanopyrrolidine-1-carbonyl)pyrrolidin-3-ylamino)nicotinonitrile::6-[(3R,5S)-5-((S)-2-Cyano-pyrrolidine-1-carbonyl)-pyrrolidin-3-ylamino]-nicotinonitrile::CHEMBL192165

SMILES: O=C([C@@H]1C[C@H](CN1)Nc1ccc(cn1)C#N)N1CCC[C@H]1C#N

InChI Key: InChIKey=DNRULGSPUYABLM-RDBSUJKOSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50166314   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50166314 (6-((3S,5S)-5-((S)-2-cyanopyrrolidine-1-carbonyl)py...) Show SMILES O=C([C@@H]1C[C@H](CN1)Nc1ccc(cn1)C#N)N1CCC[C@H]1C#N Show InChI InChI=1S/C16H18N6O/c17-7-11-3-4-15(20-9-11)21-12-6-14(19-10-12)16(23)22-5-1-2-13(22)8-18/h3-4,9,12-14,19H,1-2,5-6,10H2,(H,20,21)/t12-,13+,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Inhibitory concentration against human dipeptidyl-peptidase IV				Bioorg Med Chem Lett 15: 2441-5 (2005) Article DOI: 10.1016/j.bmcl.2005.03.077 BindingDB Entry DOI: 10.7270/Q27P8XWJ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50166314 (6-((3S,5S)-5-((S)-2-cyanopyrrolidine-1-carbonyl)py...) Show SMILES O=C([C@@H]1C[C@H](CN1)Nc1ccc(cn1)C#N)N1CCC[C@H]1C#N Show InChI InChI=1S/C16H18N6O/c17-7-11-3-4-15(20-9-11)21-12-6-14(19-10-12)16(23)22-5-1-2-13(22)8-18/h3-4,9,12-14,19H,1-2,5-6,10H2,(H,20,21)/t12-,13+,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of DPP4 in human plasma by fluorescence assay				Bioorg Med Chem 15: 641-55 (2006) Article DOI: 10.1016/j.bmc.2006.10.059 BindingDB Entry DOI: 10.7270/Q21N81X1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase IV (Rattus norvegicus (rat))	BDBM50166314 (6-((3S,5S)-5-((S)-2-cyanopyrrolidine-1-carbonyl)py...) Show SMILES O=C([C@@H]1C[C@H](CN1)Nc1ccc(cn1)C#N)N1CCC[C@H]1C#N Show InChI InChI=1S/C16H18N6O/c17-7-11-3-4-15(20-9-11)21-12-6-14(19-10-12)16(23)22-5-1-2-13(22)8-18/h3-4,9,12-14,19H,1-2,5-6,10H2,(H,20,21)/t12-,13+,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Inhibitory concentration against rat dipeptidyl-peptidase IV				Bioorg Med Chem Lett 15: 2441-5 (2005) Article DOI: 10.1016/j.bmcl.2005.03.077 BindingDB Entry DOI: 10.7270/Q27P8XWJ
					More data for this Ligand-Target Pair