BDBM50166515 3-[2-(2-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)-6-methyl-3H-pyrimidin-4-one::CHEMBL373306

SMILES: Cc1cc(=O)n(CCc2ccccc2F)c(n1)-c1ccccc1O

InChI Key: InChIKey=IITRZYOFELTAMW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50166515 (3-[2-(2-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES Cc1cc(=O)n(CCc2ccccc2F)c(n1)-c1ccccc1O Show InChI InChI=1S/C19H17FN2O2/c1-13-12-18(24)22(11-10-14-6-2-4-8-16(14)20)19(21-13)15-7-3-5-9-17(15)23/h2-9,12,23H,10-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair