BDBM50166534 4-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-butyramide::CHEMBL364463

SMILES: NCCCC(=O)N[C@H](Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1ccccc1CNCCc1cccs1

InChI Key: InChIKey=LDKZCTCDXVIBCI-HHHXNRCGSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50166534 (4-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-...) Show SMILES NCCCC(=O)N[C@H](Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1ccccc1CNCCc1cccs1 Show InChI InChI=1S/C30H37Cl2N5O2S/c31-24-10-9-22(26(32)20-24)19-27(35-29(38)8-3-12-33)30(39)37-16-14-36(15-17-37)28-7-2-1-5-23(28)21-34-13-11-25-6-4-18-40-25/h1-2,4-7,9-10,18,20,27,34H,3,8,11-17,19,21,33H2,(H,35,38)/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]-NDP-MSH as radioligand				Bioorg Med Chem Lett 15: 2541-6 (2005) Article DOI: 10.1016/j.bmcl.2005.03.053 BindingDB Entry DOI: 10.7270/Q22Z1527
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50166534 (4-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-...) Show SMILES NCCCC(=O)N[C@H](Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1ccccc1CNCCc1cccs1 Show InChI InChI=1S/C30H37Cl2N5O2S/c31-24-10-9-22(26(32)20-24)19-27(35-29(38)8-3-12-33)30(39)37-16-14-36(15-17-37)28-7-2-1-5-23(28)21-34-13-11-25-6-4-18-40-25/h1-2,4-7,9-10,18,20,27,34H,3,8,11-17,19,21,33H2,(H,35,38)/t27-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity for melanocortin-3 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligand				Bioorg Med Chem Lett 15: 2541-6 (2005) Article DOI: 10.1016/j.bmcl.2005.03.053 BindingDB Entry DOI: 10.7270/Q22Z1527
					More data for this Ligand-Target Pair