BDBM50166670 2-{5-[3-(Pyridin-2-ylamino)-propoxy]-indol-1-ylmethyl}-pentanoic acid::CHEMBL436333
SMILES: CCCC(Cn1ccc2cc(OCCCNc3ccccn3)ccc12)C(O)=O
InChI Key: InChIKey=MWWBELOYBXUAQS-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ITGAV/ITGB3 (Homo sapiens (Human)) | BDBM50166670 (2-{5-[3-(Pyridin-2-ylamino)-propoxy]-indol-1-ylmet...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson, Pharmaceutical Research and Development, L.L.C. Curated by ChEMBL | Assay Description Inhibitory concentration against alphaV-beta3 integrin | Bioorg Med Chem Lett 15: 2679-84 (2005) Article DOI: 10.1016/j.bmcl.2005.01.028 BindingDB Entry DOI: 10.7270/Q2N29Z40 | |||||||||||
More data for this Ligand-Target Pair |