BDBM50166671 3-{5-[2-(5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl)-ethylamino]-indol-1-yl}-hexanoic acid::CHEMBL192905

SMILES: CCCC(CC(O)=O)n1ccc2cc(NC(=O)Cc3ccc4CCCNc4n3)ccc12

InChI Key: InChIKey=SSONDDGKHKLNPR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166671   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ITGAV/ITGB3 (Homo sapiens (Human))	BDBM50166671 (3-{5-[2-(5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl...) Show SMILES CCCC(CC(O)=O)n1ccc2cc(NC(=O)Cc3ccc4CCCNc4n3)ccc12 Show InChI InChI=1S/C24H28N4O3/c1-2-4-20(15-23(30)31)28-12-10-17-13-18(8-9-21(17)28)26-22(29)14-19-7-6-16-5-3-11-25-24(16)27-19/h6-10,12-13,20H,2-5,11,14-15H2,1H3,(H,25,27)(H,26,29)(H,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson, Pharmaceutical Research and Development, L.L.C. Curated by ChEMBL					Assay Description Inhibitory concentration against alphaV-beta3 integrin				Bioorg Med Chem Lett 15: 2679-84 (2005) Article DOI: 10.1016/j.bmcl.2005.01.028 BindingDB Entry DOI: 10.7270/Q2N29Z40
					More data for this Ligand-Target Pair