BDBM50166672 3-{5-[2-(5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl)-ethoxy]-indol-1-yl}-propionic acid::CHEMBL192879

SMILES: OC(=O)CCn1ccc2cc(OCCc3ccc4CCCNc4n3)ccc12

InChI Key: InChIKey=GYTCJTUMBCVRAA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ITGAV/ITGB3 (Homo sapiens (Human))	BDBM50166672 (3-{5-[2-(5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl...) Show SMILES OC(=O)CCn1ccc2cc(OCCc3ccc4CCCNc4n3)ccc12 Show InChI InChI=1S/C21H23N3O3/c25-20(26)8-12-24-11-7-16-14-18(5-6-19(16)24)27-13-9-17-4-3-15-2-1-10-22-21(15)23-17/h3-7,11,14H,1-2,8-10,12-13H2,(H,22,23)(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson, Pharmaceutical Research and Development, L.L.C. Curated by ChEMBL					Assay Description Inhibitory concentration against alphaV-beta3 integrin				Bioorg Med Chem Lett 15: 2679-84 (2005) Article DOI: 10.1016/j.bmcl.2005.01.028 BindingDB Entry DOI: 10.7270/Q2N29Z40
					More data for this Ligand-Target Pair