BDBM50166681 3-(5-{2-[N-(4,5-Dihydro-1H-imidazol-2-yl)-aminooxy]-ethoxy}-indol-1-yl)-3-phenyl-propionic acid::CHEMBL191518

SMILES: OC(=O)CC(c1ccccc1)n1ccc2cc(OCCONC3=NCCN3)ccc12

InChI Key: InChIKey=IYMCWAYNJYPRLE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166681   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ITGAV/ITGB3 (Homo sapiens (Human))	BDBM50166681 (3-(5-{2-[N-(4,5-Dihydro-1H-imidazol-2-yl)-aminooxy...) Show SMILES OC(=O)CC(c1ccccc1)n1ccc2cc(OCCONC3=NCCN3)ccc12 |t:23| Show InChI InChI=1S/C22H24N4O4/c27-21(28)15-20(16-4-2-1-3-5-16)26-11-8-17-14-18(6-7-19(17)26)29-12-13-30-25-22-23-9-10-24-22/h1-8,11,14,20H,9-10,12-13,15H2,(H,27,28)(H2,23,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson, Pharmaceutical Research and Development, L.L.C. Curated by ChEMBL					Assay Description Inhibitory concentration against alphaV-beta3 integrin				Bioorg Med Chem Lett 15: 2679-84 (2005) Article DOI: 10.1016/j.bmcl.2005.01.028 BindingDB Entry DOI: 10.7270/Q2N29Z40
					More data for this Ligand-Target Pair