BDBM50166694 4-{5-[3-(Pyridin-2-ylamino)-propoxy]-indol-1-yl}-benzoic acid::CHEMBL193623

SMILES: OC(=O)c1ccc(cc1)-n1ccc2cc(OCCCNc3ccccn3)ccc12

InChI Key: InChIKey=YWHXQIYGYKETHP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ITGAV/ITGB3 (Homo sapiens (Human))	BDBM50166694 (4-{5-[3-(Pyridin-2-ylamino)-propoxy]-indol-1-yl}-b...) Show SMILES OC(=O)c1ccc(cc1)-n1ccc2cc(OCCCNc3ccccn3)ccc12 Show InChI InChI=1S/C23H21N3O3/c27-23(28)17-5-7-19(8-6-17)26-14-11-18-16-20(9-10-21(18)26)29-15-3-13-25-22-4-1-2-12-24-22/h1-2,4-12,14,16H,3,13,15H2,(H,24,25)(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson, Pharmaceutical Research and Development, L.L.C. Curated by ChEMBL					Assay Description Inhibitory concentration against alphaV-beta3 integrin				Bioorg Med Chem Lett 15: 2679-84 (2005) Article DOI: 10.1016/j.bmcl.2005.01.028 BindingDB Entry DOI: 10.7270/Q2N29Z40
					More data for this Ligand-Target Pair