BDBM50166798 CHEMBL194491::[2-(4-tert-Butyl-benzyloxy)-3-methoxy-phenyl]-pyrrolidin-1-yl-methanone

SMILES: COc1cccc(C(=O)N2CCCC2)c1OCc1ccc(cc1)C(C)(C)C

InChI Key: InChIKey=NWIGDSHQGGVRHV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166798   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50166798 (CHEMBL194491 | [2-(4-tert-Butyl-benzyloxy)-3-metho...) Show SMILES COc1cccc(C(=O)N2CCCC2)c1OCc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C23H29NO3/c1-23(2,3)18-12-10-17(11-13-18)16-27-21-19(8-7-9-20(21)26-4)22(25)24-14-5-6-15-24/h7-13H,5-6,14-16H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assay				Bioorg Med Chem Lett 15: 2943-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.093 BindingDB Entry DOI: 10.7270/Q2X929TB
					More data for this Ligand-Target Pair