BDBM50166971 CHEMBL3797445

SMILES: COc1ccc2CN(C(=O)c2c1)c1ccc(NC(=O)c2ncccc2N)cc1Cl

InChI Key: InChIKey=LXZKLGATLUDYKW-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166971   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50166971 (CHEMBL3797445) Show SMILES COc1ccc2CN(C(=O)c2c1)c1ccc(NC(=O)c2ncccc2N)cc1Cl Show InChI InChI=1S/C21H17ClN4O3/c1-29-14-6-4-12-11-26(21(28)15(12)10-14)18-7-5-13(9-16(18)22)25-20(27)19-17(23)3-2-8-24-19/h2-10H,11,23H2,1H3,(H,25,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.319	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 2915-2919 (2016) Article DOI: 10.1016/j.bmcl.2016.04.041 BindingDB Entry DOI: 10.7270/Q2348N9V
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50166971 (CHEMBL3797445) Show SMILES COc1ccc2CN(C(=O)c2c1)c1ccc(NC(=O)c2ncccc2N)cc1Cl Show InChI InChI=1S/C21H17ClN4O3/c1-29-14-6-4-12-11-26(21(28)15(12)10-14)18-7-5-13(9-16(18)22)25-20(27)19-17(23)3-2-8-24-19/h2-10H,11,23H2,1H3,(H,25,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 2915-2919 (2016) Article DOI: 10.1016/j.bmcl.2016.04.041 BindingDB Entry DOI: 10.7270/Q2348N9V
					More data for this Ligand-Target Pair