BDBM50167010 CHEMBL193460::[3-Methyl-2-(4-methyl-piperazin-1-yl)-quinolin-4-yl]-pyrrolidin-1-yl-methanone

SMILES: CN1CCN(CC1)c1nc2ccccc2c(C(=O)N2CCCC2)c1C

InChI Key: InChIKey=OSGKTFURMVRNOJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50167010 (CHEMBL193460 | [3-Methyl-2-(4-methyl-piperazin-1-y...) Show SMILES CN1CCN(CC1)c1nc2ccccc2c(C(=O)N2CCCC2)c1C Show InChI InChI=1S/C20H26N4O/c1-15-18(20(25)24-9-5-6-10-24)16-7-3-4-8-17(16)21-19(15)23-13-11-22(2)12-14-23/h3-4,7-8H,5-6,9-14H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membrane				J Med Chem 48: 3564-75 (2005) Article DOI: 10.1021/jm0493461 BindingDB Entry DOI: 10.7270/Q2HH6KTH
					More data for this Ligand-Target Pair