BDBM50167096 (4R,5S)-5-(3-Chloro-benzyl)-1-methyl-4-phenyl-pyrrolidin-2-one::CHEMBL187596

SMILES: CN1[C@@H](Cc2cccc(Cl)c2)[C@H](CC1=O)c1ccccc1

InChI Key: InChIKey=GNRGJDDXSXABJQ-SJORKVTESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167096   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estradiol 17-beta-dehydrogenase 2 (Homo sapiens (Human))	BDBM50167096 ((4R,5S)-5-(3-Chloro-benzyl)-1-methyl-4-phenyl-pyrr...) Show SMILES CN1[C@@H](Cc2cccc(Cl)c2)[C@H](CC1=O)c1ccccc1 Show InChI InChI=1S/C18H18ClNO/c1-20-17(11-13-6-5-9-15(19)10-13)16(12-18(20)21)14-7-3-2-4-8-14/h2-10,16-17H,11-12H2,1H3/t16-,17+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibitory concentration against 17 beta hydroxysteroid dehydrogenase type 2 (type II 17-beta-HSD II)				Bioorg Med Chem Lett 15: 3053-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.025 BindingDB Entry DOI: 10.7270/Q24T6HW8
					More data for this Ligand-Target Pair