BDBM50167218 (E)-3-{3-[Cyclohexanecarbonyl-(4'-methoxy-biphenyl-4-ylmethyl)-amino]-phenyl}-acrylic acid methyl ester::CHEMBL189930

SMILES: COC(=O)\C=C\c1cccc(c1)N(Cc1ccc(cc1)-c1ccc(OC)cc1)C(=O)C1CCCCC1

InChI Key: InChIKey=AFSHZFAEMZGDAP-DEDYPNTBSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167218   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile acid receptor (Homo sapiens (Human))	BDBM50167218 ((E)-3-{3-[Cyclohexanecarbonyl-(4'-methoxy-biphenyl...) Show SMILES COC(=O)\C=C\c1cccc(c1)N(Cc1ccc(cc1)-c1ccc(OC)cc1)C(=O)C1CCCCC1 Show InChI InChI=1S/C31H33NO4/c1-35-29-18-16-26(17-19-29)25-14-11-24(12-15-25)22-32(31(34)27-8-4-3-5-9-27)28-10-6-7-23(21-28)13-20-30(33)36-2/h6-7,10-21,27H,3-5,8-9,22H2,1-2H3/b20-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	89	n/a	n/a	n/a	n/a
Universidade de São Paulo Curated by ChEMBL					Assay Description Effective concentration against farnesoid X receptor (FXR)				Bioorg Med Chem Lett 15: 3119-25 (2005) Article DOI: 10.1016/j.bmcl.2005.04.017 BindingDB Entry DOI: 10.7270/Q2125S6Q
					More data for this Ligand-Target Pair