BDBM50167248 (E)-3-{3-[Cyclohexanecarbonyl-(3'-methyl-biphenyl-4-ylmethyl)-amino]-phenyl}-acrylic acid methyl ester::CHEMBL364749

SMILES: COC(=O)\C=C\c1cccc(c1)N(Cc1ccc(cc1)-c1cccc(C)c1)C(=O)C1CCCCC1

InChI Key: InChIKey=GNJHEFISHZEUPG-KNTRCKAVSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile acid receptor (Homo sapiens (Human))	BDBM50167248 ((E)-3-{3-[Cyclohexanecarbonyl-(3'-methyl-biphenyl-...) Show SMILES COC(=O)\C=C\c1cccc(c1)N(Cc1ccc(cc1)-c1cccc(C)c1)C(=O)C1CCCCC1 Show InChI InChI=1S/C31H33NO3/c1-23-8-6-12-28(20-23)26-17-14-25(15-18-26)22-32(31(34)27-10-4-3-5-11-27)29-13-7-9-24(21-29)16-19-30(33)35-2/h6-9,12-21,27H,3-5,10-11,22H2,1-2H3/b19-16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	109	n/a	n/a	n/a	n/a
Universidade de São Paulo Curated by ChEMBL					Assay Description Effective concentration against farnesoid X receptor (FXR)				Bioorg Med Chem Lett 15: 3119-25 (2005) Article DOI: 10.1016/j.bmcl.2005.04.017 BindingDB Entry DOI: 10.7270/Q2125S6Q
					More data for this Ligand-Target Pair