BDBM50167401 CHEMBL193432::sulfanilamide derivative

SMILES: Cc1ccc2OC=C3C=[N+](CCc4ccc(cc4)S(N)(=O)=O)[Zn]4(Cl)(Cl)(OC3c2c1)OC1C(=COc2ccc(C)cc12)C=[N+]4CCc1ccc(cc1)S(N)(=O)=O

InChI Key: InChIKey=VQKKLHLSJOSKNL-ZYFFGCARSA-L

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50167401   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50167401 (CHEMBL193432 | sulfanilamide derivative ) Show SMILES Cc1ccc2OC=C3C=[N+](CCc4ccc(cc4)S(N)(=O)=O)[Zn]4(Cl)(Cl)(OC3c2c1)OC1C(=COc2ccc(C)cc12)C=[N+]4CCc1ccc(cc1)S(N)(=O)=O |c:35,47,t:6,8| Show InChI InChI=1S/2C19H19N2O4S.2ClH.Zn/c2*1-13-2-7-18-17(10-13)19(22)15(12-25-18)11-21-9-8-14-3-5-16(6-4-14)26(20,23)24;;;/h2*2-7,10-12,19H,8-9H2,1H3,(H2,20,23,24);2*1H;/q2*-1;;;+6/p-2/b2*21-11+;;;	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ospedale San Lazzaro Curated by ChEMBL					Assay Description Inhibition constant against human carbonic anhydrase IX				Bioorg Med Chem Lett 15: 3096-101 (2005) Article DOI: 10.1016/j.bmcl.2005.04.055 BindingDB Entry DOI: 10.7270/Q27M07FQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50167401 (CHEMBL193432 | sulfanilamide derivative ) Show SMILES Cc1ccc2OC=C3C=[N+](CCc4ccc(cc4)S(N)(=O)=O)[Zn]4(Cl)(Cl)(OC3c2c1)OC1C(=COc2ccc(C)cc12)C=[N+]4CCc1ccc(cc1)S(N)(=O)=O |c:35,47,t:6,8| Show InChI InChI=1S/2C19H19N2O4S.2ClH.Zn/c2*1-13-2-7-18-17(10-13)19(22)15(12-25-18)11-21-9-8-14-3-5-16(6-4-14)26(20,23)24;;;/h2*2-7,10-12,19H,8-9H2,1H3,(H2,20,23,24);2*1H;/q2*-1;;;+6/p-2/b2*21-11+;;;	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ospedale San Lazzaro Curated by ChEMBL					Assay Description Inhibition constant against human carbonic anhydrase XII				Bioorg Med Chem Lett 15: 3096-101 (2005) Article DOI: 10.1016/j.bmcl.2005.04.055 BindingDB Entry DOI: 10.7270/Q27M07FQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50167401 (CHEMBL193432 | sulfanilamide derivative ) Show SMILES Cc1ccc2OC=C3C=[N+](CCc4ccc(cc4)S(N)(=O)=O)[Zn]4(Cl)(Cl)(OC3c2c1)OC1C(=COc2ccc(C)cc12)C=[N+]4CCc1ccc(cc1)S(N)(=O)=O |c:35,47,t:6,8| Show InChI InChI=1S/2C19H19N2O4S.2ClH.Zn/c2*1-13-2-7-18-17(10-13)19(22)15(12-25-18)11-21-9-8-14-3-5-16(6-4-14)26(20,23)24;;;/h2*2-7,10-12,19H,8-9H2,1H3,(H2,20,23,24);2*1H;/q2*-1;;;+6/p-2/b2*21-11+;;;	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ospedale San Lazzaro Curated by ChEMBL					Assay Description Inhibition constant against human carbonic anhydrase II				Bioorg Med Chem Lett 15: 3096-101 (2005) Article DOI: 10.1016/j.bmcl.2005.04.055 BindingDB Entry DOI: 10.7270/Q27M07FQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50167401 (CHEMBL193432 | sulfanilamide derivative ) Show SMILES Cc1ccc2OC=C3C=[N+](CCc4ccc(cc4)S(N)(=O)=O)[Zn]4(Cl)(Cl)(OC3c2c1)OC1C(=COc2ccc(C)cc12)C=[N+]4CCc1ccc(cc1)S(N)(=O)=O |c:35,47,t:6,8| Show InChI InChI=1S/2C19H19N2O4S.2ClH.Zn/c2*1-13-2-7-18-17(10-13)19(22)15(12-25-18)11-21-9-8-14-3-5-16(6-4-14)26(20,23)24;;;/h2*2-7,10-12,19H,8-9H2,1H3,(H2,20,23,24);2*1H;/q2*-1;;;+6/p-2/b2*21-11+;;;	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ospedale San Lazzaro Curated by ChEMBL					Assay Description Inhibition constant against human carbonic anhydrase I				Bioorg Med Chem Lett 15: 3096-101 (2005) Article DOI: 10.1016/j.bmcl.2005.04.055 BindingDB Entry DOI: 10.7270/Q27M07FQ
					More data for this Ligand-Target Pair