BDBM50167475 6,8-dioxa-14-azatetracyclo[10.3.1.02,10.05,9]hexadeca-2,4,9-trien-7-one::CHEMBL190754

SMILES: O=c1oc2ccc3C4CNCC(C4)Cc3c2o1

InChI Key: InChIKey=DXXNAIKGDBZSSY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167475   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor Alpha-4/Beta-2 (Homo sapiens (Human))	BDBM50167475 (6,8-dioxa-14-azatetracyclo[10.3.1.02,10.05,9]hexad...) Show SMILES O=c1oc2ccc3C4CNCC(C4)Cc3c2o1 Show InChI InChI=1S/C13H13NO3/c15-13-16-11-2-1-9-8-3-7(5-14-6-8)4-10(9)12(11)17-13/h1-2,7-8,14H,3-6H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity against nicotinic acetylcholine receptor alpha4-beta2 in human HEK293 cells using [3H]- nicotine as radioligand				Bioorg Med Chem Lett 15: 2974-9 (2005) Article DOI: 10.1016/j.bmcl.2005.04.036 BindingDB Entry DOI: 10.7270/Q25Q4WWB
					More data for this Ligand-Target Pair