BDBM50167478 5-Pyridin-3-yl-11-aza-tricyclo[7.3.1.0*2,7*]trideca-2,4,6-triene::CHEMBL190749

SMILES: C1NCC2CC1Cc1cc(ccc21)-c1cccnc1

InChI Key: InChIKey=MMBSWSRTSFXQOO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor Alpha-4/Beta-2 (Homo sapiens (Human))	BDBM50167478 (5-Pyridin-3-yl-11-aza-tricyclo[7.3.1.0*2,7*]tridec...) Show SMILES C1NCC2CC1Cc1cc(ccc21)-c1cccnc1 Show InChI InChI=1S/C17H18N2/c1-2-14(10-18-5-1)13-3-4-17-15(8-13)6-12-7-16(17)11-19-9-12/h1-5,8,10,12,16,19H,6-7,9,11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity against nicotinic acetylcholine receptor alpha4-beta2 in human HEK293 cells using [3H]- nicotine as radioligand				Bioorg Med Chem Lett 15: 2974-9 (2005) Article DOI: 10.1016/j.bmcl.2005.04.036 BindingDB Entry DOI: 10.7270/Q25Q4WWB
					More data for this Ligand-Target Pair