BDBM50167522 CHEMBL372028::[4-(3-Aminomethyl-phenyl)-piperidin-1-yl]-(1-ethyl-1H-indol-3-yl)-methanone; TFA

SMILES: CCn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2ccccc12

InChI Key: InChIKey=ATLFSHJVPOVNMP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase (Homo sapiens (Human))	BDBM50167522 (CHEMBL372028 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES CCn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2ccccc12 Show InChI InChI=1S/C23H27N3O/c1-2-25-16-21(20-8-3-4-9-22(20)25)23(27)26-12-10-18(11-13-26)19-7-5-6-17(14-19)15-24/h3-9,14,16,18H,2,10-13,15,24H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair