BDBM50167523 CHEMBL190103::[4-(3-Aminomethyl-phenyl)-piperidin-1-yl]-(1-cyclopropylmethyl-1H-indol-3-yl)-methanone; TFA

SMILES: NCc1cccc(c1)C1CCN(CC1)C(=O)c1cn(CC2CC2)c2ccccc12

InChI Key: InChIKey=DUQNWFHMCCTXDR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase (Homo sapiens (Human))	BDBM50167523 (CHEMBL190103 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES NCc1cccc(c1)C1CCN(CC1)C(=O)c1cn(CC2CC2)c2ccccc12 Show InChI InChI=1S/C25H29N3O/c26-15-19-4-3-5-21(14-19)20-10-12-27(13-11-20)25(29)23-17-28(16-18-8-9-18)24-7-2-1-6-22(23)24/h1-7,14,17-18,20H,8-13,15-16,26H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair