BDBM50167592 6-(4-Dimethylamino-phenyl)-7-pyridin-4-yl-pyrido[2,3-d]pyrimidin-4-ylamine::CHEMBL193223

SMILES: CN(C)c1ccc(cc1)-c1cc2c(N)ncnc2nc1-c1ccncc1

InChI Key: InChIKey=JEURLXBZQRWMBJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50167592   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine kinase (Homo sapiens (Human))	BDBM50167592 (6-(4-Dimethylamino-phenyl)-7-pyridin-4-yl-pyrido[2...) Show SMILES CN(C)c1ccc(cc1)-c1cc2c(N)ncnc2nc1-c1ccncc1 Show InChI InChI=1S/C20H18N6/c1-26(2)15-5-3-13(4-6-15)16-11-17-19(21)23-12-24-20(17)25-18(16)14-7-9-22-10-8-14/h3-12H,1-2H3,(H2,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	467	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against Adenosine Kinase (enzyme)				Bioorg Med Chem Lett 15: 2803-7 (2005) Article DOI: 10.1016/j.bmcl.2005.03.098 BindingDB Entry DOI: 10.7270/Q2G160CH
					More data for this Ligand-Target Pair
Adenosine kinase (Homo sapiens (Human))	BDBM50167592 (6-(4-Dimethylamino-phenyl)-7-pyridin-4-yl-pyrido[2...) Show SMILES CN(C)c1ccc(cc1)-c1cc2c(N)ncnc2nc1-c1ccncc1 Show InChI InChI=1S/C20H18N6/c1-26(2)15-5-3-13(4-6-15)16-11-17-19(21)23-12-24-20(17)25-18(16)14-7-9-22-10-8-14/h3-12H,1-2H3,(H2,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against Adenosine Kinase (intact cells)				Bioorg Med Chem Lett 15: 2803-7 (2005) Article DOI: 10.1016/j.bmcl.2005.03.098 BindingDB Entry DOI: 10.7270/Q2G160CH
					More data for this Ligand-Target Pair