BDBM50167627 4-{(Z)-1-Carboxy-2-[4-(2-iodo-phenoxy)-phenyl]-vinylcarbamoyl}-butyric acid::CHEMBL194448

SMILES: OC(=O)CCCC(=O)N\C(=C/c1ccc(Oc2ccccc2I)cc1)C(O)=O

InChI Key: InChIKey=IHKORQUJPBOIHN-VBKFSLOCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50167627 (4-{(Z)-1-Carboxy-2-[4-(2-iodo-phenoxy)-phenyl]-vin...) Show SMILES OC(=O)CCCC(=O)N\C(=C/c1ccc(Oc2ccccc2I)cc1)C(O)=O Show InChI InChI=1S/C20H18INO6/c21-15-4-1-2-5-17(15)28-14-10-8-13(9-11-14)12-16(20(26)27)22-18(23)6-3-7-19(24)25/h1-2,4-5,8-12H,3,6-7H2,(H,22,23)(H,24,25)(H,26,27)/b16-12-	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B (HCV NS5B polymerase) in Hepatitis C virus				Bioorg Med Chem Lett 15: 2812-8 (2005) Article DOI: 10.1016/j.bmcl.2005.03.106 BindingDB Entry DOI: 10.7270/Q26M36C7
					More data for this Ligand-Target Pair