BDBM50167654 (Z)-2-(2-Hydroxy-propionylamino)-3-[4-(2-iodo-phenoxy)-phenyl]-acrylic acid::CHEMBL192137

SMILES: CC(O)C(=O)N\C(=C/c1ccc(Oc2ccccc2I)cc1)C(O)=O

InChI Key: InChIKey=FOKZWUBBPCJDNY-GDNBJRDFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50167654 ((Z)-2-(2-Hydroxy-propionylamino)-3-[4-(2-iodo-phen...) Show SMILES CC(O)C(=O)N\C(=C/c1ccc(Oc2ccccc2I)cc1)C(O)=O Show InChI InChI=1S/C18H16INO5/c1-11(21)17(22)20-15(18(23)24)10-12-6-8-13(9-7-12)25-16-5-3-2-4-14(16)19/h2-11,21H,1H3,(H,20,22)(H,23,24)/b15-10-	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B (HCV NS5B polymerase) in Hepatitis C virus				Bioorg Med Chem Lett 15: 2812-8 (2005) Article DOI: 10.1016/j.bmcl.2005.03.106 BindingDB Entry DOI: 10.7270/Q26M36C7
					More data for this Ligand-Target Pair